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Nonclassical Transpeptidases of Mycobacterium tuberculosis Alter Cell Size, Morphology, the Cytosolic Matrix, Protein Localization, Virulence, and Resistance to β-Lactams
Virtually all bacteria possess a peptidoglycan layer that is essential for their growth and survival. The β-lactams, the most widely used class of antibiotics in human history, inhibit d,d-transpeptidases, which catalyze the final step in peptidoglycan biosynthesis. The existence of a second class o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993333/ https://ncbi.nlm.nih.gov/pubmed/24464457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01396-13 |
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