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Adaptation of Escherichia coli to Elevated Sodium Concentrations Increases Cation Tolerance and Enables Greater Lactic Acid Production

Adaptive evolution was employed to generate sodium (Na(+))-tolerant mutants of Escherichia coli MG1655. Four mutants with elevated sodium tolerance, designated ALS1184, ALS1185, ALS1186, and ALS1187, were independently isolated after 73 days of serial transfer in medium containing progressively grea...

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Detalhes bibliográficos
Main Authors: Wu, Xianghao, Altman, Ronni, Eiteman, Mark A., Altman, Elliot
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993293/
https://ncbi.nlm.nih.gov/pubmed/24584246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03804-13
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