Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.

The synthetic peptides DP-107 and DP-178 (T-20), derived from separate domains within the human immunodeficiency virus type 1 (HIV-1) transmembrane (TM) protein, gp4l, are stable and potent inhibitors of HIV-1 infection and fusion. Using a computer searching strategy (computerized antiviral searchin...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lambert, D M, Barney, S, Lambert, A L, Guthrie, K, Medinas, R, Davis, D E, Bucy, T, Erickson, J, Merutka, G, Petteway, S R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39932/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700906/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2186
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