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Vaccination with Leptospiral Outer Membrane Lipoprotein LipL32 Reduces Kidney Invasion of Leptospira interrogans Serovar Canicola in Hamsters

The Leptospira interrogans vaccines currently available are serovar specific and require regular booster immunizations to maintain protection of the host. In addition, a hamster challenge batch potency test is necessary to evaluate these vaccines prior to market release, requiring the use of a large...

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Detalhes bibliográficos
Main Authors: Humphryes, P. C., Weeks, M. E., AbuOun, M., Thomson, G., Núñez, A., Coldham, N. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993109/
https://ncbi.nlm.nih.gov/pubmed/24521782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00719-13
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