Expression of the C terminus of the amyloid precursor protein alters growth factor responsiveness in stably transfected PC12 cells.

The amyloid precursor protein (APP) is a molecule centrally involved in Alzheimer disease pathology, but whose normal function is still poorly understood. To investigate the consequences of increased intracellular production of various regions of APP on cellular physiology, we stably transfected PC1...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sandhu, F A, Kim, Y, Lapan, K A, Salim, M, Aliuddin, V, Zain, S B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2180
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