Expression of the C terminus of the amyloid precursor protein alters growth factor responsiveness in stably transfected PC12 cells.

The amyloid precursor protein (APP) is a molecule centrally involved in Alzheimer disease pathology, but whose normal function is still poorly understood. To investigate the consequences of increased intracellular production of various regions of APP on cellular physiology, we stably transfected PC1...

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Hlavní autoři: Sandhu, F A, Kim, Y, Lapan, K A, Salim, M, Aliuddin, V, Zain, S B
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC39931/
https://ncbi.nlm.nih.gov/pubmed/8700905
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