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Expression of the C terminus of the amyloid precursor protein alters growth factor responsiveness in stably transfected PC12 cells.

The amyloid precursor protein (APP) is a molecule centrally involved in Alzheimer disease pathology, but whose normal function is still poorly understood. To investigate the consequences of increased intracellular production of various regions of APP on cellular physiology, we stably transfected PC1...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sandhu, F A, Kim, Y, Lapan, K A, Salim, M, Aliuddin, V, Zain, S B
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39931/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2180
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