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Nutrient Signaling in Protein Homeostasis: An Increase in Quantity at the Expense of Quality

The discovery that rapamycin extends the life span of diverse organisms has triggered many studies aimed at identifying the underlying molecular mechanisms. Mammalian target of rapamycin complex 1 (mTORC1) regulates cell growth and may regulate organismal aging by controlling mRNA translation. Howev...

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Detalhes bibliográficos
Main Authors: Conn, Crystal S., Qian, Shu-Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992710/
https://ncbi.nlm.nih.gov/pubmed/23592839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003520
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