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Nutrient Signaling in Protein Homeostasis: An Increase in Quantity at the Expense of Quality
The discovery that rapamycin extends the life span of diverse organisms has triggered many studies aimed at identifying the underlying molecular mechanisms. Mammalian target of rapamycin complex 1 (mTORC1) regulates cell growth and may regulate organismal aging by controlling mRNA translation. Howev...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992710/ https://ncbi.nlm.nih.gov/pubmed/23592839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003520 |
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