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Bypass of the pre-60S ribosomal quality control as a pathway to oncogenesis
Ribosomopathies are a class of diseases caused by mutations that affect the biosynthesis and/or functionality of the ribosome. Although they initially present as hypoproliferative disorders, such as anemia, patients have elevated risk of hyperproliferative disease (cancer) by midlife. Here, this par...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992666/ https://ncbi.nlm.nih.gov/pubmed/24706786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400247111 |
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