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Uncoupling reproduction from metabolism extends chronological lifespan in yeast

Studies of replicative and chronological lifespan in Saccharomyces cerevisiae have advanced understanding of longevity in all eukaryotes. Chronological lifespan in this species is defined as the age-dependent viability of nondividing cells. To date this parameter has only been estimated under calori...

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Detalhes bibliográficos
Main Authors: Nagarajan, Saisubramanian, Kruckeberg, Arthur L., Schmidt, Karen H., Kroll, Evgueny, Hamilton, Morgan, McInnerney, Kate, Summers, Ryan, Taylor, Timothy, Rosenzweig, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992631/
https://ncbi.nlm.nih.gov/pubmed/24706810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323918111
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