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Bcl2L13 is a ceramide synthase inhibitor in glioblastoma
Therapy resistance is a major limitation to the successful treatment of cancer. Here, we identify Bcl2-like 13 (Bcl2L13), an atypical member of the Bcl-2 family, as a therapy susceptibility gene with elevated expression in solid and blood cancers, including glioblastoma (GBM). We demonstrate that mi...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992626/ https://ncbi.nlm.nih.gov/pubmed/24706805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316700111 |
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