Chargement en cours...

Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes

AIMS: Long-QT syndromes (LQTS) are mostly autosomal-dominant congenital disorders associated with a 1:1000 mutation frequency, cardiac arrest, and sudden death. We sought to use cardiomyocytes derived from human-induced pluripotency stem cells (hiPSCs) as an in vitro model to develop and evaluate ge...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Matsa, Elena, Dixon, James E., Medway, Christopher, Georgiou, Orestis, Patel, Minal J., Morgan, Kevin, Kemp, Paul J., Staniforth, Andrew, Mellor, Ian, Denning, Chris
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992427/
https://ncbi.nlm.nih.gov/pubmed/23470493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/eht067
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!