Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis

Diabetes is a major risk factor for atherosclerosis. Although atherosclerosis is initiated by deposition of cholesterol-rich lipoproteins in the artery wall, the entry of inflammatory leukocytes into lesions fuels disease progression and impairs resolution. We show that diabetic mice have increased...

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Hlavní autoři: Nagareddy, Prabhakara R., Murphy, Andrew J., Stirzaker, Roslynn A., Hu, Yunying, Yu, Shiquing, Miller, Rachel G., Ramkhelawon, Bhama, Distel, Emilie, Westerterp, Marit, Huang, Li-Shin, Schmidt, Ann Marie, Orchard, Trevor J., Fisher, Edward A., Tall, Alan R., Goldberg, Ira J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992275/
https://ncbi.nlm.nih.gov/pubmed/23663738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.04.001
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