Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity

Obesity is associated with infiltration of macrophages into adipose tissue (AT), contributing to insulin resistance and diabetes. However, relatively little is known regarding the origin of AT macrophages (ATMs). We discovered that murine models of obesity have prominent monocytosis and neutrophilia...

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Autors principals: Nagareddy, Prabhakara R., Kraakman, Michael, Masters, Seth L., Stirzaker, Roslynn A., Gorman, Darren J., Grant, Ryan W., Dragoljevic, Dragana, Hong, Eun Shil, Abdel-Latif, Ahmed, Smyth, Susan S., Choi, Sung Hee, Korner, Judith, Bornfeldt, Karin E., Fisher, Edward A., Dixit, Vishwa Deep, Tall, Alan R., Goldberg, Ira J., Murphy, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048939/
https://ncbi.nlm.nih.gov/pubmed/24807222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.03.029
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