Oxysterol-Binding Protein is a Phosphatidylinositol 4-kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking

BACKGROUND & AIMS: Positive-sense RNA viruses remodel intracellular membranes to generate specialized membrane compartments for viral replication. Several RNA viruses, including poliovirus and hepatitis C virus (HCV), require phosphatidylinositol (PI) 4-kinases for their replication. However, it...

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Autors principals: WANG, HONGLIANG, PERRY, JEFFREY W., LAURING, ADAM S., NEDDERMANN, PETRA, DE FRANCESCO, RAFFAELE, TAI, ANDREW W.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992183/
https://ncbi.nlm.nih.gov/pubmed/24512803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.02.002
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