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Role of the Alternatively Spliced Glucocorticoid Receptor Isoform GRβ in Steroid Responsiveness and Glaucoma

Glucocorticoid (GC)-induced ocular hypertension (OHT) is a serious side effect of GC therapy in susceptible individuals. This OHT is due to increased aqueous humor (AH) outflow resistance in the trabecular meshwork (TM) caused by GC-mediated changes in TM structure and function. GCs may also play a...

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Main Authors: Jain, Ankur, Wordinger, Robert J., Yorio, Thomas, Clark, Abbot F.
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991988/
https://ncbi.nlm.nih.gov/pubmed/24506296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2013.0239
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