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FK506-Binding Protein 51 Regulates Nuclear Transport of the Glucocorticoid Receptor β and Glucocorticoid Responsiveness
PURPOSE: A spliced variant of the human glucocorticoid receptor GRβ has been implicated in glucocorticoid responsiveness in glaucoma. Over-expression of the FK506-binding immunophilin FKBP51 also causes a generalized state of glucocorticoid resistance. In the present study, the roles of FKBP51 in th...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2008
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442563/ https://ncbi.nlm.nih.gov/pubmed/18326728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1279 |
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