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Absolute Determination of Single-Stranded and Self-Complementary Adeno-Associated Viral Vector Genome Titers by Droplet Digital PCR

Accurate titration of adeno-associated viral (AAV) vector genome copies is critical for ensuring correct and reproducible dosing in both preclinical and clinical settings. Quantitative PCR (qPCR) is the current method of choice for titrating AAV genomes because of the simplicity, accuracy, and robus...

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Detalhes bibliográficos
Main Authors: Lock, Martin, Alvira, Mauricio R., Chen, Shu-Jen, Wilson, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991984/
https://ncbi.nlm.nih.gov/pubmed/24328707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2013.131
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