Absolute Determination of Single-Stranded and Self-Complementary Adeno-Associated Viral Vector Genome Titers by Droplet Digital PCR

Accurate titration of adeno-associated viral (AAV) vector genome copies is critical for ensuring correct and reproducible dosing in both preclinical and clinical settings. Quantitative PCR (qPCR) is the current method of choice for titrating AAV genomes because of the simplicity, accuracy, and robus...

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Main Authors: Lock, Martin, Alvira, Mauricio R., Chen, Shu-Jen, Wilson, James M.
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2014
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991984/
https://ncbi.nlm.nih.gov/pubmed/24328707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2013.131
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