Histone Acetylation and CREB Binding Protein Are Required for Neuronal Resistance against Ischemic Injury

Epigenetic transcriptional regulation by histone acetylation depends on the balance between histone acetyltransferase (HAT) and deacetylase activities (HDAC). Inhibition of HDAC activity provides neuroprotection, indicating that the outcome of cerebral ischemia depends crucially on the acetylation s...

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Hlavní autoři: Yildirim, Ferah, Ji, Shengbo, Kronenberg, Golo, Barco, Angel, Olivares, Roman, Benito, Eva, Dirnagl, Ulrich, Gertz, Karen, Endres, Matthias, Harms, Christoph, Meisel, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991684/
https://ncbi.nlm.nih.gov/pubmed/24748101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095465
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