Histone Acetylation and CREB Binding Protein Are Required for Neuronal Resistance against Ischemic Injury

Epigenetic transcriptional regulation by histone acetylation depends on the balance between histone acetyltransferase (HAT) and deacetylase activities (HDAC). Inhibition of HDAC activity provides neuroprotection, indicating that the outcome of cerebral ischemia depends crucially on the acetylation s...

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Detalhes bibliográficos
Main Authors: Yildirim, Ferah, Ji, Shengbo, Kronenberg, Golo, Barco, Angel, Olivares, Roman, Benito, Eva, Dirnagl, Ulrich, Gertz, Karen, Endres, Matthias, Harms, Christoph, Meisel, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991684/
https://ncbi.nlm.nih.gov/pubmed/24748101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095465
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