CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum

Remodeling chromatin is essential for cAMP-regulated gene expression, necessary not only for development but also for memory storage and other enduring mental states. Histone acetylation and deacetylation mediate long-lasting forms of synaptic plasticity in Aplysia as well as cognition in mice. Here...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Levine, Amir A., Guan, Zhonghui, Barco, Angel, Xu, Shiqin, Kandel, Eric R., Schwartz, James H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323217/
https://ncbi.nlm.nih.gov/pubmed/16380431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509735102
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