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DNA demethylation in the PTEN gene promoter induced by 5-azacytidine activates PTEN expression in the MG-63 human osteosarcoma cell line

This study used the MG-63 osteosarcoma cell line to investigate the demethylation of the phosphate and tension homolog (PTEN) gene promoter and the change in PTEN gene expression levels, which are caused by the methylation inhibitor 5-azacytidine (5-Zac), and the association between the two. Differe...

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Autori principali: SONG, DEYE, NI, JIANGDONG, XIE, HONGMING, DING, MULIANG, WANG, JUN
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991544/
https://ncbi.nlm.nih.gov/pubmed/24940389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.1571
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