Association between the Polymorphism rs3217927 of CCND2 and the Risk of Childhood Acute Lymphoblastic Leukemia in a Chinese Population

CyclinD proteins, the ultimate recipients of mitogenic and oncogenic signals, play a crucial role in cell-cycle regulation. CyclinD2, one of the cyclinD family, is overexpressed in T-acute lymphoblastic leukemia (ALL) and B-cell chronic lymphocytic leukemia and involved in the pathogenesis of leukem...

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Detalhes bibliográficos
Main Authors: Zhang, Heng, Zhou, Yan, Rui, Yaoyao, Wang, Yaping, Li, Jie, Rong, Liuchen, Wang, Meilin, Tong, Na, Zhang, Zhengdong, Chen, Jing, Fang, Yongjun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990598/
https://ncbi.nlm.nih.gov/pubmed/24743557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095059
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