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TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain

Mutations in TAR DNA-binding protein 43 (TDP-43) are associated with familial forms of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Although recent studies have revealed that mutant TDP-43 in neuronal and glial cells is toxic, how mutant TDP-43 causes primarily neuronal degen...

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Bibliografske podrobnosti
Main Authors: Yan, Sen, Wang, Chuan-En, Wei, Wenjie, Gaertig, Marta A., Lai, Liangxue, Li, Shihua, Li, Xiao-Jiang
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990167/
https://ncbi.nlm.nih.gov/pubmed/24381309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt662
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