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T-cell epitope analysis using subtracted expression libraries (TEASEL): application to a 38-kDA autoantigen recognized by T cells from an insulin-dependent diabetic patient.

Studies on circulating T cells and antibodies in newly diagnosed type 1 diabetic patients and rodent models of autoimmune diabetes suggest that beta-cell membrane proteins of 38 kDa may be important molecular targets of autoimmune attack. Biochemical approaches to the isolation and identification of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Neophytou, P I, Roep, B O, Arden, S D, Muir, E M, Duinkerken, G, Kallan, A, de Vries, R R, Hutton, J C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39901/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700877/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2014
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