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Antiplatelet Effect of Clopidogrel Can Be Reduced by Calcium-Channel Blockers
PURPOSE: Clopidogrel is metabolized by the hepatic cytochrome P450 (CYP) system into its active thiol metabolite. CYP3A4 is involved in the metabolism of both clopidogrel and dihydropyridine calcium channel blockers (CCBs). A few reports have suggested an inhibitory interaction between CCBs and clop...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Yonsei University College of Medicine
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3990098/ https://ncbi.nlm.nih.gov/pubmed/24719135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2014.55.3.683 |
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