Antiplatelet Effect of Clopidogrel Can Be Reduced by Calcium-Channel Blockers

PURPOSE: Clopidogrel is metabolized by the hepatic cytochrome P450 (CYP) system into its active thiol metabolite. CYP3A4 is involved in the metabolism of both clopidogrel and dihydropyridine calcium channel blockers (CCBs). A few reports have suggested an inhibitory interaction between CCBs and clop...

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Bibliografiske detaljer
Main Authors: Seo, Kwon-Duk, Kim, Young Dae, Yoon, Young-Won, Kim, Jong-Youn, Lee, Kyung-Yul
Format: Artigo
Sprog:Inglês
Udgivet: Yonsei University College of Medicine 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990098/
https://ncbi.nlm.nih.gov/pubmed/24719135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2014.55.3.683
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