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Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation

Anchoring microtubules to the centrosome is critical for cell geometry and polarity, yet the molecular mechanism remains unknown. Here we show that the conserved human Msd1/SSX2IP is required for microtubule anchoring. hMsd1/SSX2IP is delivered to the centrosome in a centriolar satellite-dependent m...

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Detalles Bibliográficos
Main Authors: Hori, Akiko, Ikebe, Chiho, Tada, Masazumi, Toda, Takashi
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989863/
https://ncbi.nlm.nih.gov/pubmed/24397932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337929
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