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Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation

Anchoring microtubules to the centrosome is critical for cell geometry and polarity, yet the molecular mechanism remains unknown. Here we show that the conserved human Msd1/SSX2IP is required for microtubule anchoring. hMsd1/SSX2IP is delivered to the centrosome in a centriolar satellite-dependent m...

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Détails bibliographiques
Auteurs principaux: Hori, Akiko, Ikebe, Chiho, Tada, Masazumi, Toda, Takashi
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989863/
https://ncbi.nlm.nih.gov/pubmed/24397932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337929
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