Determination of 3-mercaptopyruvate in rabbit plasma by high performance liquid chromatography tandem mass spectrometry

Accidental or intentional cyanide poisoning is a serious health risk. The current suite of FDA approved antidotes, including hydroxocobalamin, sodium nitrite, and sodium thiosulfate is effective, but each antidote has specific major limitations, such as large effective dosage or delayed onset of act...

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Main Authors: Stutelberg, Michael W., Vinnakota, Chakravarthy V., Mitchell, Brendan L., Monteil, Alexandre R., Patterson, Steven E., Logue, Brian A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989840/
https://ncbi.nlm.nih.gov/pubmed/24480329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2014.01.006
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