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Carbon-Carbon Bond Cleavage in Activation of the Prodrug Nabumetone
Carbon-carbon bond cleavage reactions are catalyzed by, among others, lanosterol 14-demethylase (CYP51), cholesterol side-chain cleavage enzyme (CYP11), sterol 17β-lyase (CYP17), and aromatase (CYP19). Because of the high substrate specificities of these enzymes and the complex nature of their subst...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989788/ https://ncbi.nlm.nih.gov/pubmed/24584631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.056903 |
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