Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function

The endoplasmic reticulum (ER) Ca(2+) sensor stromal interaction molecule 1 (STIM1) has been implicated as a key mediator of store-dependent and store-independent Ca(2+) entry pathways and maintenance of ER structure. STIM1 is present in embryonic, neonatal, and adult cardiomyocytes and has been str...

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Autori principali: Collins, Helen E., He, Lan, Zou, Luyun, Qu, Jing, Zhou, Lufang, Litovsky, Silvio H., Yang, Qinglin, Young, Martin E., Marchase, Richard B., Chatham, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
Soggetti:
Rapid Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989749/
https://ncbi.nlm.nih.gov/pubmed/24585777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00075.2014
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