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Viral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength

Insulin-like growth factor I (IGF-I) is a protein that regulates and promotes growth in skeletal muscle. The IGF-I precursor polypeptide contains a COOH-terminal extension called the E-peptide. Alternative splicing in the rodent produces two isoforms, IA and IB, where the mature IGF-I in both isofor...

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Detalhes bibliográficos
Main Authors: Brisson, Becky K., Spinazzola, Janelle, Park, SooHyun, Barton, Elisabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989742/
https://ncbi.nlm.nih.gov/pubmed/24569593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00008.2014
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