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Mature IGF-I excels in promoting functional muscle recovery from disuse atrophy compared with pro-IGF-IA

Prolonged disuse of skeletal muscle results in atrophy, and once physical activity is resumed, there is increased susceptibility to injury. Insulin-like growth factor-I (IGF-I) is considered a potential therapeutic target to attenuate atrophy during unloading and to enhance rehabilitation upon reloa...

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Detalhes bibliográficos
Main Authors: Park, SooHyun, Brisson, Becky K., Liu, Min, Spinazzola, Janelle M., Barton, Elisabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972750/
https://ncbi.nlm.nih.gov/pubmed/24371018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00955.2013
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