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Direct evidence of intracrine angiotensin II signaling in neurons

The existence of a local renin-angiotensin system (RAS) in neurons was first postulated 40 years ago. Further studies indicated intraneuronal generation of ANG II. However, the function and signaling mechanisms of intraneuronal ANG II remained elusive. Since ANG II type 1 receptor (AT(1)R) is the ma...

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Detalhes bibliográficos
Main Authors: Deliu, Elena, Brailoiu, G. Cristina, Eguchi, Satoru, Hoffman, Nicholas E., Rabinowitz, Joseph E., Tilley, Douglas G., Madesh, Muniswamy, Koch, Walter J., Brailoiu, Eugen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989719/
https://ncbi.nlm.nih.gov/pubmed/24401846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00131.2013
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