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Intracellular Endothelin Type B Receptor-driven Ca(2+) Signal Elicits Nitric Oxide Production in Endothelial Cells

Endothelin-1 exerts its actions via activation of ET(A) and ET(B) G(q/11) protein-coupled receptors, located in the plasmalemma, cytoplasm, and nucleus. Although the autocrine/paracrine nature of endothelin-1 signaling has been extensively studied, its intracrine role has been largely attributed to...

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Autores principales: Deliu, Elena, Brailoiu, G. Cristina, Mallilankaraman, Karthik, Wang, Hong, Madesh, Muniswamy, Undieh, Ashiwel S., Koch, Walter J., Brailoiu, Eugen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510805/
https://ncbi.nlm.nih.gov/pubmed/23086942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418533
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