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Computational modeling of anoctamin 1 calcium-activated chloride channels as pacemaker channels in interstitial cells of Cajal

Interstitial cells of Cajal (ICC) act as pacemaker cells in the gastrointestinal tract by generating electrical slow waves to regulate rhythmic smooth muscle contractions. Intrinsic Ca(2+) oscillations in ICC appear to produce the slow waves by activating pacemaker currents, currently thought to be...

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Detalhes bibliográficos
Main Authors: Lees-Green, Rachel, Gibbons, Simon J., Farrugia, Gianrico, Sneyd, James, Cheng, Leo K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989704/
https://ncbi.nlm.nih.gov/pubmed/24481603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00449.2013
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