SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion

Synaptic vesicles fuse with the plasma membrane in response to Ca(2+) influx, thereby releasing neurotransmitters into the synaptic cleft. The protein machinery that mediates this process, consisting of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) and regulatory pr...

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Autori principali: Bharat, Tanmay A M, Malsam, Jörg, Hagen, Wim J H, Scheutzow, Andrea, Söllner, Thomas H, Briggs, John A G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
Soggetti:
Scientific Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989697/
https://ncbi.nlm.nih.gov/pubmed/24493260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337807
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