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TBC1D5 and the AP2 complex regulate ATG9 trafficking and initiation of autophagy
The RabGAP protein TBC1D5 controls cellular endomembrane trafficking processes and binds the retromer subunit VPS29 and the ubiquitin-like protein ATG8 (LC3). Here, we describe that TBC1D5 also associates with ATG9 and the active ULK1 complex during autophagy. Moreover, ATG9 and TBC1D5 interact with...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Backwell Publishing Ltd
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989670/ https://ncbi.nlm.nih.gov/pubmed/24603492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337995 |
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