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Neuroligin-1 knockdown reduces survival of adult-generated newborn hippocampal neurons

Survival of adult-born hippocampal granule cells is modulated by neural activity, and thought to be enhanced by excitatory synaptic signaling. Here, we report that a reduction in the synaptogenic protein neuroligin-1 in adult-born neurons in vivo decreased their survival, but surprisingly, this effe...

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Autori principali: Schnell, Eric, Long, Thomas H., Bensen, AeSoon L., Washburn, Eric K., Westbrook, Gary L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989658/
https://ncbi.nlm.nih.gov/pubmed/24782702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00071
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