Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake

Mitochondrial calcium uptake is a critical event in various cellular activities. Two recently identified proteins, the mitochondrial Ca(2+) uniporter (MCU), which is the pore-forming subunit of a Ca(2+) channel, and mitochondrial calcium uptake 1 (MICU1), which is the regulator of MCU, are essential...

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Bibliographic Details
Main Authors: Wang, Lele, Yang, Xue, Li, Siwei, Wang, Zheng, Liu, Yu, Feng, Jianrong, Zhu, Yushan, Shen, Yuequan
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989653/
https://ncbi.nlm.nih.gov/pubmed/24514027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386523
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