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Arrestin makes T cells stop and become active

T-cell activation requires signaling by T-cell receptors (TCRs) that bind antigen on the antigen-presenting cells (APCs) at the immunological synapse (IS). Sustained signaling requires continuous supply of new TCRs to the IS. In this issue of The EMBO Journal, Fernández-Arenas et al (2014) describe...

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Autors principals: Gurevich, Vsevolod V, Gurevich, Eugenia V
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989646/
https://ncbi.nlm.nih.gov/pubmed/24502974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387724
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