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Co-regulation proteomics reveals substrates and mechanisms of APC/C-dependent degradation
Using multiplexed quantitative proteomics, we analyzed cell cycle-dependent changes of the human proteome. We identified >4,400 proteins, each with a six-point abundance profile across the cell cycle. Hypothesizing that proteins with similar abundance profiles are co-regulated, we clustered the p...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989644/ https://ncbi.nlm.nih.gov/pubmed/24510915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201385876 |
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