FAK dimerization controls its kinase-dependent functions at focal adhesions

Focal adhesion kinase (FAK) controls adhesion-dependent cell motility, survival, and proliferation. FAK has kinase-dependent and kinase-independent functions, both of which play major roles in embryogenesis and tumor invasiveness. The precise mechanisms of FAK activation are not known. Using x-ray c...

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Detalhes bibliográficos
Main Authors: Brami-Cherrier, Karen, Gervasi, Nicolas, Arsenieva, Diana, Walkiewicz, Katarzyna, Boutterin, Marie-Claude, Ortega, Alvaro, Leonard, Paul G, Seantier, Bastien, Gasmi, Laila, Bouceba, Tahar, Kadaré, Gress, Girault, Jean-Antoine, Arold, Stefan T
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989642/
https://ncbi.nlm.nih.gov/pubmed/24480479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386399
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