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Mutational Landscape of the Essential Autophagy Gene BECN1 in Human Cancers
Evidence suggests that the catabolic process of macroautophagy (autophagy hereafter) can either suppress or promote cancer. The essential autophagy gene ATG6/BECN1 encoding the Beclinl protein has been implicated as a haploinsufficient tumor suppressor in breast, ovarian and prostate cancers. The pr...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989371/ https://ncbi.nlm.nih.gov/pubmed/24478461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0614 |
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