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Gene Targeting of Mouse Tardbp Negatively Affects Masp2 Expression

Amyotrophic Lateral Sclerosis (ALS) is a devastating adult onset neurodegenerative disease affecting both upper and lower motor neurons. TDP-43, encoded by the TARDBP gene, was identified as a component of motor neuron cytoplasmic inclusions in both familial and sporadic ALS and has become a patholo...

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Detalhes bibliográficos
Main Authors: Dib, Samar, Xiao, Shangxi, Miletic, Denise, Robertson, Janice
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989299/
https://ncbi.nlm.nih.gov/pubmed/24740308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095373
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