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Advantages and pitfalls in the application of mixed model association methods

Mixed linear models are emerging as a method of choice for conducting genetic association studies in humans and other organisms. The advantages of mixed linear model association (MLMA) include preventing false-positive associations due to population or relatedness structure, and increasing power by...

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Detalhes bibliográficos
Main Authors: Yang, Jian, Zaitlen, Noah A., Goddard, Michael E., Visscher, Peter M., Price, Alkes L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989144/
https://ncbi.nlm.nih.gov/pubmed/24473328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2876
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