Preservation of micro-architecture and angiogenic potential in a pulmonary acellular matrix obtained using intermittent intra-tracheal flow of detergent enzymatic treatment

Tissue engineering of autologous lung tissue aims to become a therapeutic alternative to transplantation. Efforts published so far in creating scaffolds have used harsh decellularization techniques that damage the extracellular matrix (ECM), deplete its components and take up to 5 weeks to perform....

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Main Authors: Maghsoudlou, Panagiotis, Georgiades, Fanourios, Tyraskis, Athanasios, Totonelli, Giorgia, Loukogeorgakis, Stavros P., Orlando, Giuseppe, Shangaris, Panicos, Lange, Peggy, Delalande, Jean-Marie, Burns, Alan J., Cenedese, Angelo, Sebire, Neil J., Turmaine, Mark, Guest, Brogan N., Alcorn, John F., Atala, Anthony, Birchall, Martin A., Elliott, Martin J., Eaton, Simon, Pierro, Agostino, Gilbert, Thomas W., De Coppi, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988964/
https://ncbi.nlm.nih.gov/pubmed/23727263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.05.015
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