Optimization of Liver Decellularization Maintains Extracellular Matrix Micro-Architecture and Composition Predisposing to Effective Cell Seeding

Hepatic tissue engineering using decellularized scaffolds is a potential therapeutic alternative to conventional transplantation. However, scaffolds are usually obtained using decellularization protocols that destroy the extracellular matrix (ECM) and hamper clinical translation. We aim to develop a...

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Udgivet i:PLoS One
Main Authors: Maghsoudlou, Panagiotis, Georgiades, Fanourios, Smith, Holly, Milan, Anna, Shangaris, Panicos, Urbani, Luca, Loukogeorgakis, Stavros P., Lombardi, Benedetta, Mazza, Giuseppe, Hagen, Charlotte, Sebire, Neil J., Turmaine, Mark, Eaton, Simon, Olivo, Alessandro, Godovac-Zimmermann, Jasminka, Pinzani, Massimo, Gissen, Paul, De Coppi, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861300/
https://ncbi.nlm.nih.gov/pubmed/27159223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155324
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