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GABAergic circuit dysfunction in the Drosophila Fragile X syndrome model
Fragile X syndrome (FXS), caused by loss of FMR1 gene function, is the most common heritable cause of intellectual disability and autism spectrum disorders. The FMR1 protein (FMRP) translational regulator mediates activity-dependent control of synapses. In addition to the metabotropic glutamate rece...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988906/ https://ncbi.nlm.nih.gov/pubmed/24423648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.01.008 |
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