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GABAergic circuit dysfunction in the Drosophila Fragile X syndrome model

Fragile X syndrome (FXS), caused by loss of FMR1 gene function, is the most common heritable cause of intellectual disability and autism spectrum disorders. The FMR1 protein (FMRP) translational regulator mediates activity-dependent control of synapses. In addition to the metabotropic glutamate rece...

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Detalhes bibliográficos
Main Authors: Gatto, Cheryl L., Pereira, Daniel, Broadie, Kendal
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988906/
https://ncbi.nlm.nih.gov/pubmed/24423648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.01.008
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