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Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase

Fragile X syndrome (FXS), caused by loss of the fragile X mental retardation 1 (FMR1) product (FMRP), is the most common cause of inherited intellectual disability and autism spectrum disorders. FXS patients suffer multiple behavioral symptoms, including hyperactivity, disrupted circadian cycles, an...

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Библиографические подробности
Главные авторы: Siller, Saul S., Broadie, Kendal
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Limited 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180232/
https://ncbi.nlm.nih.gov/pubmed/21669931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008045
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